Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety

Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety

Advancements in rheumatoid arthritis (RA) treatment protocols and introduction of targeted biological therapies have markedly improved patient outcomes, despite this, up to 50% of patients still fail to achieve a significant clinical response. In veterinary medicine, stem cell therapy in the form of autologous stromal vascular fraction (SVF) is an accepted therapeutic modality for degenerative ...

Safety Analysis of Autologous Stem Cell Therapy in a Variety of Degenerative Diseases and Injuries Using the Stromal Vascular Fraction

BACKGROUND Stem cells from adipose tissue offer a novel therapy for patients with damaged tissue. Stromal vascular fraction (SVF) injected into patients may reduce inflammation, promote healing, and repair damaged/scarred tissue. SVF can be isolated from fat (adipose) tissue in an outpatient procedure. The SVF population includes mesenchymal stem cells (MSCs), pericytes, endothelial/progenitor ...

Semi-automated extraction of stromal vascular fraction for autologous cell therapy

Safety of stromal vascular fraction cells applications in chronic pain

Autologous stromal vascular fraction (SVF) can be enzymatically released from lipoaspirate obtained under local anesthesia. SVF is known to have regenerative, anti-inflammatory, pain mitigating, and immune-modulatory properties. Our translational research network has been studying the safety and efficacy of SVF since 2012. Almost 100 related physician teams around the world are applying the sam...

Surgery in Rheumatoid Arthritis Effects of Synovectomy and Application of Autologous Vaccine

Early Synovectomy is advisable for rheum­atoid arthritis. An autologus vaccine from the excised synovia can be prepared from the tis-­ sues and given to the patient for at least 2 years or even longer in order to arrest the di­sease and for prevent relapse.  The patient can be taught to give himself his own vaccine two times weekly. While there is possibility of an antianaphylactic reaction. F...